9-POHSA

9-POHSA
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity. Structurally, these esters are comprised of a C-16 or C-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) linked to either a C-16 or C-18 hydroxy substituent. 9-POHSA is a form of FAHFA in which palmitoleic acid is esterified at the 9th carbon of hydroxy stearic acid. Among the FAHFA family members, The levels of POHSA are significantly elevated in serum of glucose tolerant AG4OX mice, which overexpress the Glut4 glucose transporter specifically in adipose tissue. As other FAHFAs improve glucose tolerance, stimulate insulin secretion, and have anti-inflammatory effects, 9-POHSA may be a bioactive lipid with roles in metabolic syndrome and inflammation.

Information

1481636-43-4 >98% C 34 H 64 O 4 536.88 FA3024 9-(9Z-hexadecenoyloxy)-octadecanoic acid, 9-(palmitoleoyloxy)stearic acid CCCCCCCCCC(OC(CCCCCCC/C=C\CCCCCC)=O)CCCCCCCC(O)=O VCXRHEIVUHPWLL-SEYXRHQNSA-N
Size Price Availability
10mg $99.00
25mg $235.00
100mg $675.00
250mg $1,305.00
1g $1,999.00
  • $99.00
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Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity. Structurally, these esters are comprised of a C-16 or C-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) linked to either a C-16 or C-18 hydroxy substituent. 9-POHSA is a form of FAHFA in which palmitoleic acid is esterified at the 9th carbon of hydroxy stearic acid. Among the FAHFA family members, The levels of POHSA are significantly elevated in serum of glucose tolerant AG4OX mice, which overexpress the Glut4 glucose transporter specifically in adipose tissue. As other FAHFAs improve glucose tolerance, stimulate insulin secretion, and have anti-inflammatory effects, 9-POHSA may be a bioactive lipid with roles in metabolic syndrome and inflammation.

Information

1481636-43-4 >98% C 34 H 64 O 4 536.88 FA3024 9-(9Z-hexadecenoyloxy)-octadecanoic acid, 9-(palmitoleoyloxy)stearic acid CCCCCCCCCC(OC(CCCCCCC/C=C\CCCCCC)=O)CCCCCCCC(O)=O VCXRHEIVUHPWLL-SEYXRHQNSA-N