Cholic Acid L-Phenylalanine Conjugate

Cholic Acid L-Phenylalanine Conjugate

Recently reported in Nature, new bile acid conjugates were discovered in murine and human intestines made by gut microbiota that stimulate the farnesoid receptor (FXR).

Cholic acid, also known as 3α,7α,12α-trihydroxy-5β-cholan-24-oic acid is a primary bile acid. Cholic acid, along with chenodeoxycholic acid, is one of the two major bile acids produced by the liver, where it is synthesized from cholesterol. Usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.

Information

Not Assigned >97% C 33 H 49 N O 6 555.76 S1008 Cholic acid phenylalanine adduct, Phe-chol O[C@@H]1CC[C@]2(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@]([C@H](C)CCC(N[C@@H](CC5=CC=CC=C5)C(O)=O)=O)([H])CC[C@@]4([H])[C@]3([H])[C@H](O)C[C@@]([H])2C1 IQKZHEVJCMKOED-RYHSAYMFSA-N
Size Price Availability
10mg $169.00
25mg $335.00
100mg $740.00
250mg $1,189.00
1g $1,619.00
  • $169.00
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Recently reported in Nature, new bile acid conjugates were discovered in murine and human intestines made by gut microbiota that stimulate the farnesoid receptor (FXR).

Cholic acid, also known as 3α,7α,12α-trihydroxy-5β-cholan-24-oic acid is a primary bile acid. Cholic acid, along with chenodeoxycholic acid, is one of the two major bile acids produced by the liver, where it is synthesized from cholesterol. Usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.

Information

Not Assigned >97% C 33 H 49 N O 6 555.76 S1008 Cholic acid phenylalanine adduct, Phe-chol O[C@@H]1CC[C@]2(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@]([C@H](C)CCC(N[C@@H](CC5=CC=CC=C5)C(O)=O)=O)([H])CC[C@@]4([H])[C@]3([H])[C@H](O)C[C@@]([H])2C1 IQKZHEVJCMKOED-RYHSAYMFSA-N